Product Description

Bonitar 400mg Tablet contains the active constituent bosutinib. It is used to treat a type of blood cancer called Philadelphia chromosome-positive chronic myelogenous leukemia (Ph+ CML) in adult patients who are newly diagnosed or for whom other medicines have either not worked or not suitable. Philadelphia chromosome-positive chronic myelogenous leukemia is a blood cancer in which the body produces too many of a specific kind of white blood cell called granulocytes. 

Talk to your doctor if you have heart problems, kidney disorders, liver disorders, infections, or diarrhea before taking Bonitar 400mg Tablet. Limit your time outside and use sunscreen if you must go outside as this medicine can make you more sensitive to the sun or UV rays. Do not eat or drink grapefruit containing food products as this may increase the risk of side effects. Use effective birth control during the treatment and for at least one month after the last dose. 

How to use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it.

Uses

Treatment of Blood cancer

Side Effects

Serious:

• Blood disorders (bleeding, fever, bruising)
• Stomach problems (stomach pain, vomiting, diarrhea, constipation, nausea)
• Hepatitis B reactivation
• Severe skin reactions
• Liver problems (yellowing of white part of eyes and skin, tea-colored urine)
• Heart problems (loss of consciousness, irregular heartbeat)

Common:

• Low blood cell count
• Headache, dizziness
• Cough, shortness of breath
• Joint pain, back pain
• Decreased appetite
• Respiratory tract infection
• Increase in blood pressure
• Ringing in the ears
• Itching, acne
• Dehydration

Storage

Store below 30℃